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The CD226/TIGIT axis is involved in T cell hypo-responsiveness appearance in long-term kidney transplant recipients

T cell exhaustion refers to a dysfunctional state in which effector T cells present a decreased ability to proliferate and to produce cytokines, while the co-expression of inhibitory receptors increases. We investigated global and donor-specific T cell responses in a cohort of stable, living-donor k...

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Detalles Bibliográficos
Autores principales: Del Bello, Arnaud, Gouin, Anna, Chaubet, Camille, Kamar, Nassim, Treiner, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276733/
https://www.ncbi.nlm.nih.gov/pubmed/35821240
http://dx.doi.org/10.1038/s41598-022-15705-6