An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination

Endogenous DNA double-strand breaks (DSBs) occurring in neural cells have been implicated in the pathogenesis of neurodevelopmental disorders (NDDs). Currently, a genomic map of endogenous DSBs arising during human neurogenesis is missing. Here, we applied in-suspension Breaks Labeling In Situ and S...

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Detalles Bibliográficos
Autores principales: Ballarino, Roberto, Bouwman, Britta A. M., Agostini, Federico, Harbers, Luuk, Diekmann, Constantin, Wernersson, Erik, Bienko, Magda, Crosetto, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276747/
https://www.ncbi.nlm.nih.gov/pubmed/35821502
http://dx.doi.org/10.1038/s41597-022-01508-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276747/
https://www.ncbi.nlm.nih.gov/pubmed/35821502
http://dx.doi.org/10.1038/s41597-022-01508-x

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