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Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by (68)Ga-FAPI-PET imaging

BACKGROUND: In colorectal cancer (CRC), the consensus molecular subtype 4 (CMS4) is associated with therapy resistance and poor prognosis. Clinical diagnosis of CMS4 is hampered by locoregional and temporal variables influencing CMS classification. Diagnostic tools that comprehensively detect CMS4 a...

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Detalles Bibliográficos
Autores principales: Strating, Esther, Wassenaar, Emma, Verhagen, Mathijs, Rauwerdink, Paulien, van Schelven, Susanne, de Hingh, Ignace, Rinkes, Inne Borel, Boerma, Djamila, Witkamp, Arjen, Lacle, Miangela, Fodde, Riccardo, Volckmann, Richard, Koster, Jan, Stedingk, Kris, Giesel, Frederik, de Roos, Remmert, Poot, Alex, Bol, Guus, Lam, Marnix, Elias, Sjoerd, Kranenburg, Onno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276750/
https://www.ncbi.nlm.nih.gov/pubmed/35296803
http://dx.doi.org/10.1038/s41416-022-01748-z