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Extracellular Nucleosomes Accelerate Microglial Inflammation via C-Type Lectin Receptor 2D and Toll-Like Receptor 9 in mPFC of Mice With Chronic Stress

Damage-associated molecular patterns (DAMPs) are the primary promoter of progressive neuroinflammation and are associated with chronic stress-related emotional disorders. The present study investigated the role and mechanism of extracellular nucleosomes and histones, the newly defined DAMPs, in mice...

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Detalles Bibliográficos
Autores principales: Wu, Huanghui, Bao, Han, Liu, Cong, Zhang, Qiao, Huang, Ailing, Quan, Minxue, Li, Chunhui, Xiong, Ying, Chen, Guozhong, Hou, Lichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276970/
https://www.ncbi.nlm.nih.gov/pubmed/35844599
http://dx.doi.org/10.3389/fimmu.2022.854202