Mycophenolic Acid Induces the Intestinal Epithelial Barrier Damage through Mitochondrial ROS

Mycophenolic acid (MPA) may cause gastrointestinal adverse effects by damaging the intestinal epithelial barrier, the underlying mechanisms remain elusive. Studies have demonstrated that oxidative stress caused by reactive oxygen species (ROS) is linked to tight junction (TJ) proteins and apoptosis,...

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Detalles Bibliográficos
Autores principales: Deng, Yiyun, Zhang, Zhe, Yang, Hui, Wang, Jing, Feng, Lijuan, Su, Yong, Xu, Dujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277164/
https://www.ncbi.nlm.nih.gov/pubmed/35847589
http://dx.doi.org/10.1155/2022/4195699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277164/
https://www.ncbi.nlm.nih.gov/pubmed/35847589
http://dx.doi.org/10.1155/2022/4195699

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