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Mycophenolic Acid Induces the Intestinal Epithelial Barrier Damage through Mitochondrial ROS
Mycophenolic acid (MPA) may cause gastrointestinal adverse effects by damaging the intestinal epithelial barrier, the underlying mechanisms remain elusive. Studies have demonstrated that oxidative stress caused by reactive oxygen species (ROS) is linked to tight junction (TJ) proteins and apoptosis,...
Autores principales: | Deng, Yiyun, Zhang, Zhe, Yang, Hui, Wang, Jing, Feng, Lijuan, Su, Yong, Xu, Dujuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277164/ https://www.ncbi.nlm.nih.gov/pubmed/35847589 http://dx.doi.org/10.1155/2022/4195699 |
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