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Activation of the P62-Keap1-NRF2 Pathway Protects against Ferroptosis in Radiation-Induced Lung Injury

Radiation-induced lung injury (RILI) is one of the most common, serious, and dose-limiting toxicities of thoracic radiotherapy. A primary cause for this is the radiation-induced cell death. Ferroptosis is a recently recognized form of regulated cell death, characterized by the accumulation of lipid...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Chen, Jingyao, Yuan, Sujuan, Zhuang, Xibing, Qiao, Tiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277166/
https://www.ncbi.nlm.nih.gov/pubmed/35847598
http://dx.doi.org/10.1155/2022/8973509