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Inference and uncertainty quantification of stochastic gene expression via synthetic models

Estimating uncertainty in model predictions is a central task in quantitative biology. Biological models at the single-cell level are intrinsically stochastic and nonlinear, creating formidable challenges for their statistical estimation which inevitably has to rely on approximations that trade accu...

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Detalles Bibliográficos
Autores principales: Öcal, Kaan, Gutmann, Michael U., Sanguinetti, Guido, Grima, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277240/
https://www.ncbi.nlm.nih.gov/pubmed/35858045
http://dx.doi.org/10.1098/rsif.2022.0153