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PAX5 alterations in an infant case of KMT2A‐rearranged leukemia with lineage switch

Lineage switch is a rare event at leukemic relapse. While mostly known to occur in KMT2A‐rearranged infant leukemia, the underlying mechanism is yet to be depicted. This case report describes a female infant who achieved remission of KMT2A‐MLLT3‐rearranged acute monocytic leukemia, but 6 months ther...

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Detalles Bibliográficos
Autores principales: Nakajima, Koji, Kubota, Hirohito, Kato, Itaru, Isobe, Kiyotaka, Ueno, Hiroo, Kozuki, Kagehiro, Tanaka, Kuniaki, Kawabata, Naoko, Mikami, Takashi, Tamefusa, Kosuke, Nishiuchi, Ritsuo, Saida, Satoshi, Umeda, Katsutsugu, Hiramatsu, Hidefumi, Adachi, Souichi, Takita, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277256/
https://www.ncbi.nlm.nih.gov/pubmed/35467057
http://dx.doi.org/10.1111/cas.15380