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Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets

Infants with neonatal cholestasis are prone to neurodevelopmental deficits, however, the underlying pathogenesis is unclear. Lipid malabsorption and accumulation of potentially neurotoxic molecules in the blood such as bile acids are important yet relatively unexplored pathways. Here, we developed a...

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Detalles Bibliográficos
Autores principales: Henriksen, Nicole Lind, Hansen, Svend Høime, Lycas, Matthew Domenic, Pan, Xiaoyu, Eriksen, Thomas, Johansen, Lars Søndergaard, Sprenger, Richard R., Ejsing, Christer Stenby, Burrin, Douglas G., Skovgaard, Kerstin, Christensen, Vibeke Brix, Thymann, Thomas, Pankratova, Stanislava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277266/
https://www.ncbi.nlm.nih.gov/pubmed/35822260
http://dx.doi.org/10.14814/phy2.15368