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Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis

Histone deacetylase 6 (HDAC6), a deacetylase of p53, has emerged as a privileged inhibitory target for cancer therapy because of its deacetylating activity for p53 at K120 and K373/382. However, intricate roles of HDAC6 in hepatocellular carcinogenesis have been suggested by recent evidence, namely...

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Detalles Bibliográficos
Autores principales: Phorl, Sophors, Memon, Azra, Seo, Yuri, Hoang, Thi Oanh, Tran, Trung Nghia, Nguyen, Le Minh Tri, Lee, Chang Hoon, Lee, Woon Kyu, Lee, Joo‐Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277267/
https://www.ncbi.nlm.nih.gov/pubmed/35534985
http://dx.doi.org/10.1111/cas.15391