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Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins
BACKGROUND: For effective tumor elimination, cytotoxic CD8(+) T cells must recognize tumor-derived antigens presented on class I major histocompatibility complex (MHC-I). Despite a general association between the expression of immunogenic antigens, typically neoantigens, and response to immunotherap...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277371/ https://www.ncbi.nlm.nih.gov/pubmed/35820727 http://dx.doi.org/10.1136/jitc-2021-004159 |