Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins

BACKGROUND: For effective tumor elimination, cytotoxic CD8(+) T cells must recognize tumor-derived antigens presented on class I major histocompatibility complex (MHC-I). Despite a general association between the expression of immunogenic antigens, typically neoantigens, and response to immunotherap...

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Detalles Bibliográficos
Autores principales: Fessenden, Tim B, Stopfer, Lauren E, Chatterjee, Fiona, Zulueta, Julian, Mesfin, Josh, Cordero Dumit, Therese, Reijers, Irene, Hoefsmit, Esmee P, Blank, Christian, White, Forest, Spranger, Stefani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277371/
https://www.ncbi.nlm.nih.gov/pubmed/35820727
http://dx.doi.org/10.1136/jitc-2021-004159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277371/
https://www.ncbi.nlm.nih.gov/pubmed/35820727
http://dx.doi.org/10.1136/jitc-2021-004159

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