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Mitigation of Ionizing Radiation-Induced Gastrointestinal Damage by Insulin-Like Growth Factor-1 in Mice

Purpose: Insulin-like growth factor-1 (IGF-1) stimulates epithelial regeneration but may also induce life-threatening hypoglycemia. In our study, we first assessed its safety. Subsequently, we examined the effect of IGF-1 administered in different dose regimens on gastrointestinal damage induced by...

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Detalles Bibliográficos
Autores principales: Pejchal, Jaroslav, Tichy, Ales, Kmochova, Adela, Fikejzlova, Lenka, Kubelkova, Klara, Milanova, Marcela, Lierova, Anna, Filipova, Alzbeta, Muckova, Lubica, Cizkova, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277384/
https://www.ncbi.nlm.nih.gov/pubmed/35847048
http://dx.doi.org/10.3389/fphar.2022.663855