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Intensifying Continuous Production of Gag-HA VLPs at High Cell Density Using Stable Insect Cells Adapted to Low Culture Temperature

Protein production processes based on stable insect cell lines require intensification to be competitive with the insect cell-baculovirus expression vector system (IC-BEVS). High cell density (HCD) cultures operate continuously, capable of maintaining specific production rates for extended periods o...

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Detalles Bibliográficos
Autores principales: Fernandes, Bárbara, Correia, Ricardo, Alves, Paula M., Roldão, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277389/
https://www.ncbi.nlm.nih.gov/pubmed/35845394
http://dx.doi.org/10.3389/fbioe.2022.917746