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Human PERK rescues unfolded protein response-deficient yeast cells
Protein folding and quality control is tightly regulated at the endoplasmic reticulum (ER), and its disruption is associated with many diseases. In eukaryotes, the accumulation of unfolded protein in the ER is sensed by the three sensors, IRE1, PERK, and ATF6 to activate the unfolded protein respons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277465/ https://www.ncbi.nlm.nih.gov/pubmed/35845817 http://dx.doi.org/10.17912/micropub.biology.000592 |