The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

The intestinal hormone, glucose-dependent insulinotropic polypeptide (GIP), is involved in important physiological functions, including postprandial blood glucose homeostasis, bone remodeling, and lipid metabolism. While mutations leading to physiological changes can be identified in large-scale seq...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, Jacek, Holst, Jens Juul, Hauser, Alexander Sebastian, Rosenkilde, Mette Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277503/
https://www.ncbi.nlm.nih.gov/pubmed/35846282
http://dx.doi.org/10.3389/fendo.2022.891586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277503/
https://www.ncbi.nlm.nih.gov/pubmed/35846282
http://dx.doi.org/10.3389/fendo.2022.891586

Ejemplares similares