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The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection
The intestinal hormone, glucose-dependent insulinotropic polypeptide (GIP), is involved in important physiological functions, including postprandial blood glucose homeostasis, bone remodeling, and lipid metabolism. While mutations leading to physiological changes can be identified in large-scale seq...
Autores principales: | Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, Jacek, Holst, Jens Juul, Hauser, Alexander Sebastian, Rosenkilde, Mette Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277503/ https://www.ncbi.nlm.nih.gov/pubmed/35846282 http://dx.doi.org/10.3389/fendo.2022.891586 |
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