Extracellular CIRP Promotes GPX4-Mediated Ferroptosis in Sepsis

Sepsis is characterized by life-threatening organ dysfunction caused by a dysregulated host response to infection. Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern (DAMP) that promotes inflammation and induces cell death via apoptosis, NETosis, and/or...

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Detalles Bibliográficos
Autores principales: Shimizu, Junji, Murao, Atsushi, Nofi, Colleen, Wang, Ping, Aziz, Monowar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277504/
https://www.ncbi.nlm.nih.gov/pubmed/35844517
http://dx.doi.org/10.3389/fimmu.2022.903859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277504/
https://www.ncbi.nlm.nih.gov/pubmed/35844517
http://dx.doi.org/10.3389/fimmu.2022.903859

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