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Extracellular CIRP Promotes GPX4-Mediated Ferroptosis in Sepsis
Sepsis is characterized by life-threatening organ dysfunction caused by a dysregulated host response to infection. Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern (DAMP) that promotes inflammation and induces cell death via apoptosis, NETosis, and/or...
Autores principales: | Shimizu, Junji, Murao, Atsushi, Nofi, Colleen, Wang, Ping, Aziz, Monowar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277504/ https://www.ncbi.nlm.nih.gov/pubmed/35844517 http://dx.doi.org/10.3389/fimmu.2022.903859 |
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