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CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development

Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse model allowing expression of both the fluorescent protein tdTomato and the CRE recombinase selectivel...

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Detalles Bibliográficos
Autores principales: Tchen, John, Simon, Quentin, Chapart, Léa, Pellefigues, Christophe, Karasuyama, Hajime, Miyake, Kensuke, Blank, Ulrich, Benhamou, Marc, Daugas, Eric, Charles, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277511/
https://www.ncbi.nlm.nih.gov/pubmed/35844602
http://dx.doi.org/10.3389/fimmu.2022.900532