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Pharmacological and Genetic Inhibition of HDAC4 Alleviates Renal Injury and Fibrosis in Mice

Histone deacetylase 4 (HDAC4) has been shown to be involved in cell proliferation, differentiation, and migration and is associated with a variety of cancers. However, the role of HDAC4 in renal fibrogenesis and its mechanisms are unclear. We assessed the role of HDAC4 and possible mechanisms of fib...

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Detalles Bibliográficos
Autores principales: Shen, Fengchen, Hou, Xiying, Li, Tingting, Yu, Jianjun, Chen, Huizhen, Liu, Na, Qiu, Andong, Zhuang, Shougang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277565/
https://www.ncbi.nlm.nih.gov/pubmed/35847036
http://dx.doi.org/10.3389/fphar.2022.929334