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Targeted protein degradation using deGradFP in Trypanosoma brucei

Targeted protein degradation is an invaluable tool in studying the function of proteins. Such a tool was not available in Trypanosoma brucei, an evolutionarily divergent eukaryote that causes human African trypanosomiasis. Here, we have adapted deGradFP (degrade green fluorescent protein [GFP]), a p...

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Detalles Bibliográficos
Autores principales: Ishii, Midori, Akiyoshi, Bungo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277568/
https://www.ncbi.nlm.nih.gov/pubmed/35865221
http://dx.doi.org/10.12688/wellcomeopenres.17964.2