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Spatial and Temporal Resolution of the Oxygen-Independent Photoinduced DNA Interstrand Cross-Linking by a Nitroimidazole Derivative

[Image: see text] DNA damage is ubiquitous in nature and is at the basis of emergent treatments such as photodynamic therapy, which is based on the activation of highly oxidative reactive oxygen species by photosensitizing O(2). However, hypoxia observed in solid tumors imposes the necessity to devi...

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Detalles Bibliográficos
Autores principales: Abdelgawwad, Abdelazim M. A., Monari, Antonio, Tuñón, Iñaki, Francés-Monerris, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277591/
https://www.ncbi.nlm.nih.gov/pubmed/35771238
http://dx.doi.org/10.1021/acs.jcim.2c00460