A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes

Pemigatinib (PMB) is a small molecule inhibitor of fibroblast growth factor receptor 1 (FGFR1), FGFR2 and FGFR3. On April 17, 2020, the US Food and Drug Administration granted accelerated approval for PMB for the treatment of adults with previously treated, unresectable metastatic or locally advance...

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Detalles Bibliográficos
Autores principales: Attwa, Mohamed W., Abdelhameed, Ali S., Alsaif, Nawaf A., Kadi, Adnan A., AlRabiah, Haitham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277622/
https://www.ncbi.nlm.nih.gov/pubmed/35919584
http://dx.doi.org/10.1039/d2ra02885a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277622/
https://www.ncbi.nlm.nih.gov/pubmed/35919584
http://dx.doi.org/10.1039/d2ra02885a

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