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Supratherapeutic Tacrolimus Concentrations With Nirmatrelvir/Ritonavir in Solid Organ Transplant Recipients Requiring Hospitalization: A Case Series Using Rifampin for Reversal

Nirmatrelvir/ritonavir was recently granted emergency use authorization for mild to moderate coronavirus disease 2019. Drug–drug interactions between ritonavir and tacrolimus are underappreciated by nontransplant providers. We describe 2 solid organ transplant recipients prescribed nirmatrelvir/rito...

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Detalles Bibliográficos
Autores principales: Rose, Dusten T, Gandhi, Saurin M, Bedard, Rachael A, Mondy, Kristin E, Chu, Alexander L, Gamble, Kelly C, Gee, Amanda T, Kundra, Monica A, Williams, Amber L, Lee, Brian K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277654/
https://www.ncbi.nlm.nih.gov/pubmed/35854994
http://dx.doi.org/10.1093/ofid/ofac238