DNA Damage Increases Secreted Aβ(40) and Aβ(42) in Neuronal Progenitor Cells: Relevance to Alzheimer’s Disease

BACKGROUND: Recent studies suggest a strong association between neuronal DNA damage, elevated levels of amyloid-β (Aβ), and regions of the brain that degenerate in Alzheimer’s disease (AD). OBJECTIVE: To investigate the nature of this association, we tested the hypothesis that extensive DNA damage l...

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Detalles Bibliográficos
Autores principales: Welty, Starr, Thathiah, Amantha, Levine, Arthur Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277680/
https://www.ncbi.nlm.nih.gov/pubmed/35570488
http://dx.doi.org/10.3233/JAD-220030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277680/
https://www.ncbi.nlm.nih.gov/pubmed/35570488
http://dx.doi.org/10.3233/JAD-220030

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