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DNA Damage Increases Secreted Aβ(40) and Aβ(42) in Neuronal Progenitor Cells: Relevance to Alzheimer’s Disease

BACKGROUND: Recent studies suggest a strong association between neuronal DNA damage, elevated levels of amyloid-β (Aβ), and regions of the brain that degenerate in Alzheimer’s disease (AD). OBJECTIVE: To investigate the nature of this association, we tested the hypothesis that extensive DNA damage l...

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Detalles Bibliográficos
Autores principales:	Welty, Starr, Thathiah, Amantha, Levine, Arthur Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277680/ https://www.ncbi.nlm.nih.gov/pubmed/35570488 http://dx.doi.org/10.3233/JAD-220030

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