Druggable genetic targets in endometrial cancer

BACKGROUND: FBXW7 is frequently somatically mutated in grade 3 endometrioid endometrial cancers (G3EECs) and serous endometrial cancers (SECs), high-risk cancers associated with poor prognosis. CRISPR-edited cell lines identified the proteomic and phosphoproteomic effects of FBXW7 mutation in 3 high...

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Detalles Bibliográficos
Autores principales: Lehrer, Steven, Rheinstein, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277713/
https://www.ncbi.nlm.nih.gov/pubmed/34933203
http://dx.doi.org/10.1016/j.ctarc.2021.100502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277713/
https://www.ncbi.nlm.nih.gov/pubmed/34933203
http://dx.doi.org/10.1016/j.ctarc.2021.100502

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