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MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

BACKGROUND: Studies have suggested that many down-regulated miRNAs identified in the brain tissue or serum of Alzheimer’s disease (AD) patients were involved in the formation of senile plaques and neurofibrillary tangles. Specifically, our previous study revealed that microRNA-22-3p (miR-22-3p) was...

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Detalles Bibliográficos
Autores principales: Xia, Pengcheng, Chen, Jing, Liu, Yingchao, Cui, Xiaolin, Wang, Cuicui, Zong, Shuai, Wang, Le, Lu, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277852/
https://www.ncbi.nlm.nih.gov/pubmed/35821145
http://dx.doi.org/10.1186/s12974-022-02548-1