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A functional reference map of the RNF8 interactome in cancer

BACKGROUND: RNF8 is an E3 ligase identified as a critical DNA damage-responsive protein. Recently, multiple reports have shown that RNF8 could be used as an important therapeutic target for cancer chemo/radiotherapy. However, the understanding of RNF8 remains limited due to the lack of its interacto...

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Detalles Bibliográficos
Autores principales: Liu, Chuanyang, Kuang, Jingyu, Wang, Yuxuan, Duan, Ting, Min, Lu, Lu, Chenyu, Zhang, Tianyi, Chen, Ruifen, Wu, Ying, Zhu, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277853/
https://www.ncbi.nlm.nih.gov/pubmed/35831895
http://dx.doi.org/10.1186/s13062-022-00331-z