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The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice

BACKGROUND: Ubiquitination is a post-translational modification required for a number of physiological functions regulating protein homeostasis, such as protein degradation. The endoplasmic reticulum (ER) quality control system recognizes and degrades proteins no longer needed in the ER through the...

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Detalles Bibliográficos
Autores principales: Nozawa, Kaori, Fujihara, Yoshitaka, Devlin, Darius J., Deras, Ricardo E., Kent, Katarzyna, Larina, Irina V., Umezu, Kohei, Yu, Zhifeng, Sutton, Courtney M., Ye, Qiuji, Dean, Laura K., Emori, Chihiro, Ikawa, Masahito, Garcia, Thomas X., Matzuk, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277888/
https://www.ncbi.nlm.nih.gov/pubmed/35831855
http://dx.doi.org/10.1186/s12915-022-01368-2