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A novel E-cadherin/SOX9 axis regulates cancer stem cells in multiple myeloma by activating Akt and MAPK pathways

Cancer stem cells (CSCs) have been identified in multiple myeloma (MM) and are widely regarded as a key driver of MM initiation and progression. E-cadherin, in addition to its established role as a marker for epithelial-mesenchymal transition, also plays critical roles in controlling the aggressive...

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Detalles Bibliográficos
Autores principales: Samart, Parinya, Rojanasakul, Yon, Issaragrisil, Surapol, Luanpitpong, Sudjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277902/
https://www.ncbi.nlm.nih.gov/pubmed/35831838
http://dx.doi.org/10.1186/s40164-022-00294-x