Metformin attenuates the production and proliferative effects of prolactin induced by medroxyprogesterone acetate during fertility-sparing treatment for endometrial cancer

BACKGROUND: Progestin is used for fertility-sparing treatment in cases of endometrial cancer (EC). Progestin can induce hyperprolactinemia by increasing pituitary secretion and endometrial decidualization. However, progestin induces prolactin (PRL) secretion, which stimulates cell proliferation and...

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Detalles Bibliográficos
Autores principales: Gu, Wenjing, Mitsuhashi, Akira, Kobayashi, Tatsuya, Shozu, Makio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277913/
https://www.ncbi.nlm.nih.gov/pubmed/35820883
http://dx.doi.org/10.1186/s12885-022-09858-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277913/
https://www.ncbi.nlm.nih.gov/pubmed/35820883
http://dx.doi.org/10.1186/s12885-022-09858-w

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