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A novel nitidine chloride nanoparticle overcomes the stemness of CD133(+)EPCAM(+) Huh7 hepatocellular carcinoma cells for liver cancer therapy

BACKGROUND: Stemness of CD133(+)EPCAM(+) hepatocellular carcinoma cells ensures cancer resistance to apoptosis,which is a challenge to current liver cancer treatments. In this study, we evaluated the tumorcidal activity of a novel nanoparticle of nitidine chloride (TPGS-FA/NC, TPGS-FA: folic acid mo...

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Detalles Bibliográficos
Autores principales: Li, Danni, Zhang, Qiying, Zhou, Yuzhu, Zhu, Hua, Li, Tong, Du, Fangkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277916/
https://www.ncbi.nlm.nih.gov/pubmed/35820920
http://dx.doi.org/10.1186/s40360-022-00589-z