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StackEPI: identification of cell line-specific enhancer–promoter interactions based on stacking ensemble learning

BACKGROUND: Understanding the regulatory role of enhancer–promoter interactions (EPIs) on specific gene expression in cells contributes to the understanding of gene regulation, cell differentiation, etc., and its identification has been a challenging task. On the one hand, using traditional wet expe...

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Detalles Bibliográficos
Autores principales: Fan, Yongxian, Peng, Binchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277947/
https://www.ncbi.nlm.nih.gov/pubmed/35820811
http://dx.doi.org/10.1186/s12859-022-04821-9