The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration

BACKGROUND: Peripheral nerve injuries stimulate the regenerative capacity of injured neurons through a neuroimmune phenomenon termed the conditioning lesion (CL) response. This response depends on macrophage accumulation in affected dorsal root ganglia (DRGs) and peripheral nerves. The macrophage ch...

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Detalles Bibliográficos
Autores principales: Talsma, Aaron D., Niemi, Jon P., Pachter, Joel S., Zigmond, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277969/
https://www.ncbi.nlm.nih.gov/pubmed/35820932
http://dx.doi.org/10.1186/s12974-022-02497-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277969/
https://www.ncbi.nlm.nih.gov/pubmed/35820932
http://dx.doi.org/10.1186/s12974-022-02497-9

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