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Vitamin D and interferon-γ co-operate to increase the ACE-2 receptor expression in primary cultures of human thyroid cells

BACKGROUND: A more severe course of COVID-19 was associated with low levels of Vitamin D (VitD). Moreover in vitro data showed that VitD up-regulates the mRNA of the Angiotensin Converting Enzyme 2 (ACE-2), the SARS-COV-2 receptor in different type of cells. ACE-2 is expressed in several type of tis...

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Detalles Bibliográficos
Autores principales: Coperchini, F., Greco, A., Denegri, M., Ripepi, F. A., Grillini, B., Bertini, J., Calì, B., Villani, L., Magri, F., Croce, L., Gaetano, C., Cappelli, C., Trimboli, P., Chiovato, L., Rotondi, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277975/
https://www.ncbi.nlm.nih.gov/pubmed/35829990
http://dx.doi.org/10.1007/s40618-022-01857-9