An integrated understanding of the evolutionary and structural features of the SARS-CoV-2 spike receptor binding domain (RBD)

Conventional drug development strategies typically use pocket in protein structures as drug-target sites. They overlook the plausible effects of protein evolvability and resistant mutations on protein structure which in turn may impair protein-drug interaction. In this study, we used an integrated e...

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Detalles Bibliográficos
Autores principales: Sanyal, Dwipanjan, Banerjee, Suharto, Bej, Aritra, Chowdhury, Vaidehi Roy, Uversky, Vladimir N., Chowdhury, Sourav, Chattopadhyay, Krishnananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278002/
https://www.ncbi.nlm.nih.gov/pubmed/35841961
http://dx.doi.org/10.1016/j.ijbiomac.2022.07.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278002/
https://www.ncbi.nlm.nih.gov/pubmed/35841961
http://dx.doi.org/10.1016/j.ijbiomac.2022.07.022

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