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Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data

Multiple methods have recently been developed to reconstruct full-length B-cell receptors (BCRs) from single-cell RNA sequencing (scRNA-seq) data. This need emerged from the expansion of scRNA-seq techniques, the increasing interest in antibody-based drug development and the importance of BCR repert...

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Detalles Bibliográficos
Autores principales: Andreani, Tommaso, Slot, Linda M, Gabillard, Samuel, Strübing, Carsten, Reimertz, Claus, Yaligara, Veeranagouda, Bakker, Aleida M, Olfati-Saber, Reza, Toes, René E M, Scherer, Hans U, Augé, Franck, Šimaitė, Deimantė
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278041/
https://www.ncbi.nlm.nih.gov/pubmed/35855325
http://dx.doi.org/10.1093/nargab/lqac049