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Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron

Bacterial sphingolipid synthesis is important for the fitness of gut commensal bacteria with an implied potential for regulating mammalian host physiology. Multiple steps in bacterial sphingolipid synthesis pathways have been characterized previously, with the first step of de novo sphingolipid synt...

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Detalles Bibliográficos
Autores principales: Lee, Min-Ting, Le, Henry H., Besler, Kevin R., Johnson, Elizabeth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278070/
https://www.ncbi.nlm.nih.gov/pubmed/35667415
http://dx.doi.org/10.1016/j.jlr.2022.100236