Adeno-Associated Virus Receptor-Binding: Flexible Domains and Alternative Conformations through Cryo-Electron Tomography of Adeno-Associated Virus 2 (AAV2) and AAV5 Complexes

Recombinant forms of adeno-associated virus (rAAV) are vectors of choice in the development of treatments for a number of genetic dispositions. Greater understanding of AAV’s molecular virology is needed to underpin needed improvements in efficiency and specificity. Recent advances have included ide...

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Detalles Bibliográficos
Autores principales: Hu, Guiqing, Silveria, Mark A., Zane, Grant M., Chapman, Michael S., Stagg, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Structure and Assembly
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278096/
https://www.ncbi.nlm.nih.gov/pubmed/35674430
http://dx.doi.org/10.1128/jvi.00106-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278096/
https://www.ncbi.nlm.nih.gov/pubmed/35674430
http://dx.doi.org/10.1128/jvi.00106-22

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