SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19

Brains of 42 COVID-19 decedents and 107 non-COVID-19 controls were studied. RT-PCR screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral sequences in 7 regions (2.5% of 320 samples), concentrated in 4/20 subjects (20%). Additional screening of olfactory bulb (OB), amygdala...

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Detalles Bibliográficos
Autores principales: Serrano, Geidy E, Walker, Jessica E, Tremblay, Cécilia, Piras, Ignazio S, Huentelman, Matthew J, Belden, Christine M, Goldfarb, Danielle, Shprecher, David, Atri, Alireza, Adler, Charles H, Shill, Holly A, Driver-Dunckley, Erika, Mehta, Shyamal H, Caselli, Richard, Woodruff, Bryan K, Haarer, Chadwick F, Ruhlen, Thomas, Torres, Maria, Nguyen, Steve, Schmitt, Dasan, Rapscak, Steven Z, Bime, Christian, Peters, Joseph L, Alevritis, Ellie, Arce, Richard A, Glass, Michael J, Vargas, Daisy, Sue, Lucia I, Intorcia, Anthony J, Nelson, Courtney M, Oliver, Javon, Russell, Aryck, Suszczewicz, Katsuko E, Borja, Claryssa I, Cline, Madison P, Hemmingsen, Spencer J, Qiji, Sanaria, Hobgood, Holly M, Mizgerd, Joseph P, Sahoo, Malaya K, Zhang, Haiyu, Solis, Daniel, Montine, Thomas J, Berry, Gerald J, Reiman, Eric M, Röltgen, Katharina, Boyd, Scott D, Pinsky, Benjamin A, Zehnder, James L, Talbot, Pierre, Desforges, Marc, DeTure, Michael, Dickson, Dennis W, Beach, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278252/
https://www.ncbi.nlm.nih.gov/pubmed/35818336
http://dx.doi.org/10.1093/jnen/nlac056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278252/
https://www.ncbi.nlm.nih.gov/pubmed/35818336
http://dx.doi.org/10.1093/jnen/nlac056

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