Cargando…

Optimized Protocols for In-Vitro T-Cell-Dependent and T-Cell-Independent Activation for B-Cell Differentiation Studies Using Limited Cells

BACKGROUND/METHODS: For mechanistic studies, in-vitro human B-cell differentiation and generation of plasma cells are invaluable techniques. However, the heterogeneity of both T-cell-dependent (TD) and T-cell-independent (TI) stimuli and the disparity of culture conditions used in existing protocols...

Descripción completa

Detalles Bibliográficos
Autores principales: Marsman, Casper, Verhoeven, Dorit, Koers, Jana, Rispens, Theo, ten Brinke, Anja, van Ham, S. Marieke, Kuijpers, Taco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278277/
https://www.ncbi.nlm.nih.gov/pubmed/35844625
http://dx.doi.org/10.3389/fimmu.2022.815449