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Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome

Gene expression is in part controlled by cis-regulatory elements (CREs) such as enhancers and repressive elements. Anecdotal evidence has indicated that a CRE and a promoter need to be biochemically compatible for promoter regulation to occur, but this compatibility has remained poorly characterized...

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Detalles Bibliográficos
Autores principales: Martinez-Ara, Miguel, Comoglio, Federico, van Arensbergen, Joris, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278412/
https://www.ncbi.nlm.nih.gov/pubmed/35594855
http://dx.doi.org/10.1016/j.molcel.2022.04.009