Implementing polymeric pseudorotaxanes for boosting corneal permeability and antiaspergillus activity of tolnaftate: formulation development, statistical optimization, ex vivo permeation and in vivo assessment

Fungal keratitis (FK) is a devastating ocular disease that can cause corneal opacity and blindness if not treated effectively. Tolnaftate (TOL) is a selective fungicidal drug against Aspergillus spp. which are among the most common causes of mycotic keratitis. TOL is lipophilic drug with low water s...

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Detalles Bibliográficos
Autores principales: Aziz, Diana, Mohamed, Sally, Tayel, Saadia, Makhlouf, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278446/
https://www.ncbi.nlm.nih.gov/pubmed/35815689
http://dx.doi.org/10.1080/10717544.2022.2094499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278446/
https://www.ncbi.nlm.nih.gov/pubmed/35815689
http://dx.doi.org/10.1080/10717544.2022.2094499

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