Dyhidro-β-agarofurans natural and synthetic as acetylcholinesterase and COX inhibitors: interaction with the peripheral anionic site (AChE-PAS), and anti-inflammatory potentials

In order to find molecules of natural origin with potential biological activities, we isolate and synthesise compounds with agarofuran skeletons (epoxyeudesmanes). From the seeds of Maytenus disticha and Maytenus magellanica we obtained six dihydro-β-agarofurans, and by means of the Robinson annulat...

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Detalles Bibliográficos
Autores principales: Alarcón-Enos, Julio, Muñoz-Núñez, Evelyn, Gutiérrez, Margarita, Quiroz-Carreño, Soledad, Pastene-Navarrete, Edgar, Céspedes Acuña, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278454/
https://www.ncbi.nlm.nih.gov/pubmed/35815566
http://dx.doi.org/10.1080/14756366.2022.2091554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278454/
https://www.ncbi.nlm.nih.gov/pubmed/35815566
http://dx.doi.org/10.1080/14756366.2022.2091554

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