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Investigating Celastrol's Anti-DCM Targets and Mechanisms via Network Pharmacology and Experimental Validation

METHODS: Data from TCMSP and GEO databases were utilized to identify targets for Celastrol on DCM. The relationship between the major targets and conventional glycolipid metabolism was obtained with Spearman correlation analysis. Experiments on animals were conducted utilizing healthy control (HC),...

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Detalles Bibliográficos
Autores principales: Xi, Rui, Wan, Yongxin, Yang, Lihong, Zhang, Jingying, Yang, Liu, Yang, Shuai, Chai, Rui, Mu, Fengchen, Sun, Qiting, Yan, Rui, Wu, Zhifang, Li, Sijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278495/
https://www.ncbi.nlm.nih.gov/pubmed/35845929
http://dx.doi.org/10.1155/2022/7382130