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Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa
The drug/proton antiporter MexB is the engine of the major efflux pump MexAB-OprM in Pseudomonas aeruginosa. This protein is known to transport a large variety of compounds, including antibiotics, thus conferring a multi-drug resistance phenotype. Due to the difficulty of producing co-crystals, only...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278589/ https://www.ncbi.nlm.nih.gov/pubmed/35766032 http://dx.doi.org/10.1039/d2cp00951j |