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Validation of Bromodomain and Extraterminal proteins as therapeutic targets in neurofibromatosis type 2
BACKGROUND: Neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disease characterized by development of schwannomas on the VIIIth (vestibular) cranial nerves. Bromodomain and extra-terminal domain (BET) proteins regulate gene transcription and their activity is required in a variety of c...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278623/ https://www.ncbi.nlm.nih.gov/pubmed/35855490 http://dx.doi.org/10.1093/noajnl/vdac072 |